{"id":5499,"date":"2020-03-18T16:29:00","date_gmt":"2020-03-18T15:29:00","guid":{"rendered":"https:\/\/saccosystem.com\/?post_type=news&#038;p=5499"},"modified":"2024-12-11T16:44:01","modified_gmt":"2024-12-11T15:44:01","slug":"crl-1505-vs-virus","status":"publish","type":"news","link":"https:\/\/saccosystem.com\/fr\/news\/crl-1505-vs-virus\/","title":{"rendered":"CRL 1505 Vs. Virus"},"content":{"rendered":"\n<div class=\"wp-block-group row\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-group col-lg-8\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<h2 class=\"wp-block-heading\">Probiotics have been shown to effectively reduce the incidence of respiratory tract infections (RTIs). In particular, the strain <em>Lactobacillus rhamnosus<\/em> CRL1505 has demonstrated an important capacity to keep RTIs at bay.  <\/h2>\n\n\n\n<div style=\"height:80px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>Clinical evidence<\/strong><\/h4>\n\n\n\n<div style=\"height:32px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>A randomized, double-blind, placebo-controlled trial with 298 pre-school children (2-5 years old) that consumed either yogurt containing CRL1505 (&gt;10E8 cfu\/day) or a placebo yogurt 5 days\/week for 6 months showed [1]:<\/p>\n\n\n\n<div style=\"height:48px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\"><strong><strong>Lower use of antibiotics<\/strong><\/strong><\/h4>\n\n\n\n<p><br><br><strong>A significantly reduced number of infections<\/strong> in children consuming the probiotic-containing yogurt. In particular, it lowered the incidence of: <\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>upper respiratory tract infection<\/li>\n\n\n\n<li>pharyngitis and tonsillitis<\/li>\n\n\n\n<li>acute diarrhea<\/li>\n<\/ul>\n\n\n\n<div style=\"height:48px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>In vivo, preclinical evidence<\/strong><\/h4>\n\n\n\n<div style=\"height:32px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p><strong>CRL1505 led to an earlier immune response<\/strong> and reduced lung damage when nasal challenges with different types of virus were performed [2-3].<\/p>\n\n\n\n<p>CRL1505 heightened <strong>infection resistance<\/strong> to the airway pathogen <strong><em>Streptococcus pneumoniae<\/em><\/strong> serotype 14, mice models. [4-5]<\/p>\n\n\n\n<p><strong>Heat-inactivated CRL1505 when administered intranasally<\/strong> has similar benefits to those observed when the live probiotic is administered [6].<\/p>\n\n\n\n<div style=\"height:48px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>Mechanisms of action<\/strong><\/h4>\n\n\n\n<div style=\"height:32px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>The mechanisms of action of <strong>CRL1505<\/strong> have been unveiled in a series of in vivo models, and include increased basal levels of interferon-gamma (IFN-y) in the host, a key activator of the innate and adaptive immune system, and of the anti-inflammatory cytokine interleukin 10 (IL-10) [4]. These modulations allow the priming of the immune system to tackle RTIs through an overall stimulation of the immune system, intra-and extra-intestinally [4]. <\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><br>1 Villena J, Salva S, N\u00fa\u00f1ez M, Corzo J, Tolaba R, Faedda J, Font G, Alvarez S. (2012). Probiotics for everyone! The novel immunobiotic Lactobacillus rhamnosus CRL1505 and the beginning of social probiotic programs in Argentina. International Journal of Biotechnology for Wellness Industries. 1: 189-198.<br>2 Chiba E, Tomosada Y, Vizoso-Pinto MG, Salva S, Takahashi T, Tsukida K, Kitazawa H, Alvarez S, Villena J. (2013). Immunobiotic Lactobacillus rhamnosus improves the resistance of infant mice against respiratory syncytial virus infection. International Immunopharmacology 17: 373-382.<br>3 Zelaya H, Tsukida K, Chiba E, Marranzino G, Alvarez S, Kitazawa H, Agu?ero G, Villena J. (2014). Immunobiotic lactobacilli reduce viral-associated pulmonary damage through the modulation of inflammation\u2013coagulation interactions. International Immunopharmacology 19: 161-173.<br>4 Salva S, Villena J, Alvarez S. (2010). Immunomodulatory activity of Lactobacillus rhamnosus strains isolated from goat milk: Impact on intestinal and respiratory infections. Int J Food Microbiol 141(1-2): 82-9.<br>5 Salva S, N\u00fa\u00f1ez M, Villena J, Ram\u00f3n A, Fonta G, Alvarez S. (2011). Development of a fermented goats\u2019 milk containing Lactobacillus rhamnosus: in vivo study of health benefits. J Sci Food Agric 91: 2355\u20132362.<br>6 Tomosada Y, Chiba E, Zelaya H, Takahashi T, Tsukida K, Kitazawa H, Alvarez S, Villena J. (2013). Nasally administered Lactobacillus rhamnosus strains differentially modulate respiratory antiviral immune responses and induce protection against respiratory syncytial virus infection. BMC Immunology, 14: 40.            <\/p>\n<\/div><\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group row\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-group col-lg-8\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\"><div class=\"block learn-more no-margin-top no-margin-bottom\">\n                <div class=\"col\">\n                                                                                    <div class=\"list\">\n                                    <div class=\"title\">\n                        Attached resources                    <\/div>\n                                                    <div class=\"item\">\n                                        <a href=\"https:\/\/saccosystem.com\/wp-content\/uploads\/2024\/11\/CRL-1505-vs.-VIRUS.pdf\" target=\"_blank\">\n                                            <span class=\"title\">\n                                                <span class=\"icon\">\n                                                <svg width=\"32\" height=\"32\" viewBox=\"0 0 32 32\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><mask id=\"mask0_1261_3192\" style=\"mask-type:alpha\" maskUnits=\"userSpaceOnUse\" x=\"0\" y=\"0\" width=\"32\" height=\"32\"><rect width=\"32\" height=\"32\" fill=\"#D9D9D9\"><\/rect><\/mask><g mask=\"url(#mask0_1261_3192)\"><path d=\"M7.07696 27.3332C6.4034 27.3332 5.83329 27.0998 5.36663 26.6332C4.89996 26.1665 4.66663 25.5964 4.66663 24.9228V7.07684C4.66663 6.40328 4.89996 5.83317 5.36663 5.3665C5.83329 4.89984 6.4034 4.6665 7.07696 4.6665H21.0513L27.3333 10.9485V24.9228C27.3333 25.5964 27.1 26.1665 26.6333 26.6332C26.1666 27.0998 25.5965 27.3332 24.923 27.3332H7.07696ZM7.07696 25.3332H24.923C25.0427 25.3332 25.1411 25.2947 25.218 25.2178C25.2948 25.1409 25.3333 25.0426 25.3333 24.9228V11.9998H20V6.6665H7.07696C6.95718 6.6665 6.85885 6.70495 6.78196 6.78184C6.70507 6.85873 6.66663 6.95706 6.66663 7.07684V24.9228C6.66663 25.0426 6.70507 25.1409 6.78196 25.2178C6.85885 25.2947 6.95718 25.3332 7.07696 25.3332ZM9.66663 21.9998H22.3333V19.9998H9.66663V21.9998ZM9.66663 11.9998H16V9.99984H9.66663V11.9998ZM9.66663 16.9998H22.3333V14.9998H9.66663V16.9998Z\" fill=\"#FAFAFC\"><\/path><\/g><\/svg>                                                <\/span>\n                                                <span class=\"text\">\n                                                                                                        <span class=\"description\">\n                                                        CRL 1505 vs. VIRUS                                                    <\/span>\n                                                <\/span>\n                                            <\/span>\n                                            <span class=\"action\">\n                                                                                                <span class=\"icon\">\n                                                    <svg width=\"24\" height=\"24\" viewBox=\"0 0 24 24\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n                                                        <mask id=\"mask0_1261_3199\" style=\"mask-type:alpha\" maskUnits=\"userSpaceOnUse\" x=\"0\" y=\"0\" width=\"24\" height=\"24\">\n                                                            <rect width=\"24\" height=\"24\" fill=\"#D9D9D9\"><\/rect>\n                                                        <\/mask>\n                                                        <g mask=\"url(#mask0_1261_3199)\">\n                                                            <path d=\"M12 15.7885L7.73075 11.5192L8.78475 10.4348L11.25 12.9V4.5H12.75V12.9L15.2153 10.4348L16.2693 11.5192L12 15.7885ZM6.30775 19.5C5.80258 19.5 5.375 19.325 5.025 18.975C4.675 18.625 4.5 18.1974 4.5 17.6923V14.9808H6V17.6923C6 17.7692 6.03208 17.8398 6.09625 17.9038C6.16025 17.9679 6.23075 18 6.30775 18H17.6923C17.7692 18 17.8398 17.9679 17.9038 17.9038C17.9679 17.8398 18 17.7692 18 17.6923V14.9808H19.5V17.6923C19.5 18.1974 19.325 18.625 18.975 18.975C18.625 19.325 18.1974 19.5 17.6923 19.5H6.30775Z\" fill=\"#FAFAFC\"><\/path>\n                                                        <\/g>\n                                                    <\/svg>\n                                                <\/span>\n                                                Download\n                                                                                            <\/span>\n                                        <\/a>\n                                    <\/div>\n                                            <\/div>\n                                                <\/div>\n    <\/div><\/div><\/div>\n<\/div><\/div>\n\n\n<div class=\"news-cta  no-margin-top\">\n                    <div class=\"row\">\n            <div class=\"col\">\n                <h2>\n                    Latest News                <\/h2>\n            <\/div>\n        <\/div>\n                    <\/div>\n<div class=\"news-feed\">\n    <div class=\"container no-padding\">\n        <div class=\"row\">\n            <div class=\"col\">\n                <div class=\"posts\">\n                        <div class=\"post post-extract\">\n                            <div class=\"header\">\n                                <div class=\"date\">\n                                    19 mars 2026                                <\/div>\n                                <div class=\"tag\">\n                                                                    <\/div>\n                            <\/div>\n                            <div class=\"body\">\n                                <div class=\"title\">\n                                    A regulatory achievement for Sacco System: our Heat-Inactivated CRL1505\u00ae receives GRAS status                                <\/div>\n                                <div class=\"tags\">\n                                                                    <\/div>\n                                <div class=\"text\">\n                                    <p>An important regulatory goal has been achieved with the conclusion reached by an independent expert panel for the self-affirmed GRAS (Generally Recognized as Safe) determination of our postbiotic CRL1505\u00ae HI.<\/p>\n                                <\/div>\n                            <\/div>\n                            <div class=\"footer\">\n                                <div class=\"read-more\">\n                                    <a href=\"https:\/\/saccosystem.com\/fr\/news\/a-regulatory-achievement-for-sacco-system-our-heat-inactivated-crl1505-receives-gras-status\/\">\n                                        Read Article                                    <\/a>\n                                <\/div>\n                            <\/div>\n                        <\/div>\n                        <div class=\"post post-extract\">\n                            <div class=\"header\">\n                                <div class=\"date\">\n                                    24 janvier 2026                                <\/div>\n                                <div class=\"tag\">\n                                                                    <\/div>\n                            <\/div>\n                            <div class=\"body\">\n                                <div class=\"title\">\n                                    SYNBIO\u00ae: Sacco System&rsquo;s probiotic support for healthy ageing                                <\/div>\n                                <div class=\"tags\">\n                                                                    <\/div>\n                                <div class=\"text\">\n                                    <p>The global population is ageing faster than ever before. In 2019, life expectancy at birth reached 72.8 years almost 9 years more than in 1990. In this context, staying healthy<\/p>\n                                <\/div>\n                            <\/div>\n                            <div class=\"footer\">\n                                <div class=\"read-more\">\n                                    <a href=\"https:\/\/saccosystem.com\/fr\/news\/synbio-sacco-systems-probiotic-support-for-healthy-ageing\/\">\n                                        Read Article                                    <\/a>\n                                <\/div>\n                            <\/div>\n                        <\/div>\n                        <div class=\"post post-extract\">\n                            <div class=\"header\">\n                                <div class=\"date\">\n                                    20 novembre 2025                                <\/div>\n                                <div class=\"tag\">\n                                                                    <\/div>\n                            <\/div>\n                            <div class=\"body\">\n                                <div class=\"title\">\n                                    Unveiling the survivability of probiotic CA15 strain with and without fluconazole co-administration and its effect on gut microbiota and metabolome through SHIME\u00ae model                                <\/div>\n                                <div class=\"tags\">\n                                                                    <\/div>\n                                <div class=\"text\">\n                                    <p>\u201cSurvivability of probiotic CA15 strain with and without fluconazole co-administration and its effect on gut microbiota and metabolome through SHIME\u00ae model\u201d is the title of the study that has been<\/p>\n                                <\/div>\n                            <\/div>\n                            <div class=\"footer\">\n                                <div class=\"read-more\">\n                                    <a href=\"https:\/\/saccosystem.com\/fr\/news\/lacticaseibacillus-rhamnosus-ca15-achieves-gras-status-a-milestone-for-womens-health-2\/\">\n                                        Read Article                                    <\/a>\n                                <\/div>\n                            <\/div>\n                        <\/div>\n                        <div class=\"post post-extract\">\n                            <div class=\"header\">\n                                <div class=\"date\">\n                                    07 f\u00e9vrier 2025                                <\/div>\n                                <div class=\"tag\">\n                                                                    <\/div>\n                            <\/div>\n                            <div class=\"body\">\n                                <div class=\"title\">\n                                    L. rhamnosus CA15 Achieves GRAS Status: A Milestone for Women&rsquo;s Health                                <\/div>\n                                <div class=\"tags\">\n                                                                    <\/div>\n                                <div class=\"text\">\n                                    <p>GRAS (Generally Recognised as Safe) is a designation by the US Food and Drug Administration (FDA) that indicates that a substance is considered safe based on expert consensus or a<\/p>\n                                <\/div>\n                            <\/div>\n                            <div class=\"footer\">\n                                <div class=\"read-more\">\n                                    <a href=\"https:\/\/saccosystem.com\/fr\/news\/lacticaseibacillus-rhamnosus-ca15-achieves-gras-status-a-milestone-for-womens-health\/\">\n                                        Read Article                                    <\/a>\n                                <\/div>\n                            <\/div>\n                        <\/div>\n                        <div class=\"post post-extract\">\n                            <div class=\"header\">\n                                <div class=\"date\">\n                                    08 janvier 2025                                <\/div>\n                                <div class=\"tag\">\n                                                                    <\/div>\n                            <\/div>\n                            <div class=\"body\">\n                                <div class=\"title\">\n                                    Sacco System Australia\u2019s Heat-Inactivated Postbiotics Receive Positive Recommendations from FSANZ                                <\/div>\n                                <div class=\"tags\">\n                                                                    <\/div>\n                                <div class=\"text\">\n                                    <p>Brisbane, 8 January 2025 Sacco System Australia, a leader in innovative probiotic and postbiotic solutions, is proud to announce that L. rhamnosus CRL 1505 HI (heat-inactivated) and Lactobacillus acidophilus LA1<\/p>\n                                <\/div>\n                            <\/div>\n                            <div class=\"footer\">\n                                <div class=\"read-more\">\n                                    <a href=\"https:\/\/saccosystem.com\/fr\/news\/sacco-system-australias-heat-inactivated-postbiotics-receive-positive-recommendations-from-fsanz\/\">\n                                        Read Article                                    <\/a>\n                                <\/div>\n                            <\/div>\n                        <\/div>\n                        <div class=\"post post-extract\">\n                            <div class=\"header\">\n                                <div class=\"date\">\n                                    25 novembre 2024                                <\/div>\n                                <div class=\"tag\">\n                                    News, News                                <\/div>\n                            <\/div>\n                            <div class=\"body\">\n                                <div class=\"title\">\n                                    Notre rapport de d\u00e9veloppement durable 2023 est on-line!                                <\/div>\n                                <div class=\"tags\">\n                                                                    <\/div>\n                                <div class=\"text\">\n                                    <p>Nous sommes fiers de pr\u00e9senter la cinqui\u00e8me \u00e9dition de notre rapport de durabilit\u00e9, une occasion de r\u00e9fl\u00e9chir sur les r\u00e9alisations atteintes et les d\u00e9fis \u00e0 venir&#8230;<\/p>\n                                <\/div>\n                            <\/div>\n                            <div class=\"footer\">\n                                <div class=\"read-more\">\n                                    <a href=\"https:\/\/saccosystem.com\/fr\/news\/notre-rapport-de-developpement-durable-2023-est-on-line\/\">\n                                        Read Article                                    <\/a>\n                                <\/div>\n                            <\/div>\n                        <\/div>\n                        <div class=\"post post-extract\">\n                            <div class=\"header\">\n                                <div class=\"date\">\n                                    16 avril 2024                                <\/div>\n                                <div class=\"tag\">\n                                    News                                <\/div>\n                            <\/div>\n                            <div class=\"body\">\n                                <div class=\"title\">\n                                    Sacco System is pleased to announce the grand opening of its development site in Australia.                                <\/div>\n                                <div class=\"tags\">\n                                                                    <\/div>\n                                <div class=\"text\">\n                                    <p>Today in the presence of Luna Angelini Marinucci, from 2022 the Consul of Italy in Brisbane, with territorial jurisdiction over the State of Queensland and over the Northern Territory the<\/p>\n                                <\/div>\n                            <\/div>\n                            <div class=\"footer\">\n                                <div class=\"read-more\">\n                                    <a href=\"https:\/\/saccosystem.com\/fr\/news\/sacco-system-is-pleased-to-announce-the-grand-opening-of-its-development-site-in-australia\/\">\n                                        Read Article                                    <\/a>\n                                <\/div>\n                            <\/div>\n                        <\/div>\n                        <div class=\"post post-extract\">\n                            <div class=\"header\">\n                                <div class=\"date\">\n                                    26 mars 2024                                <\/div>\n                                <div class=\"tag\">\n                                                                    <\/div>\n                            <\/div>\n                            <div class=\"body\">\n                                <div class=\"title\">\n                                    Sacco System companies have been awarded as Sustainability champions by Ecovadis                                <\/div>\n                                <div class=\"tags\">\n                                                                    <\/div>\n                                <div class=\"text\">\n                                    <p>At Sacco System we have always put Sustainability at the very core of our activities and our commitment, which is why we are proud that our companies Caglificio Clerici, Sacco<\/p>\n                                <\/div>\n                            <\/div>\n                            <div class=\"footer\">\n                                <div class=\"read-more\">\n                                    <a href=\"https:\/\/saccosystem.com\/fr\/news\/sacco-system-companies-have-been-awarded-as-sustainability-champions-by-ecovadis\/\">\n                                        Read Article                                    <\/a>\n                                <\/div>\n                            <\/div>\n                        <\/div>\n                        <div class=\"post post-extract\">\n                            <div class=\"header\">\n                                <div class=\"date\">\n                                    18 mars 2024                                <\/div>\n                                <div class=\"tag\">\n                                                                    <\/div>\n                            <\/div>\n                            <div class=\"body\">\n                                <div class=\"title\">\n                                    List Biotherapeutics and Sacco System Announce Lead Share Agreement                                <\/div>\n                                <div class=\"tags\">\n                                                                    <\/div>\n                                <div class=\"text\">\n                                    <p>Indianapolis, Ind., and Yeerongpilly, Queensland, Australia, March 13, 2024 \u2013 List Biotherapeutics, Inc. (List Bio) and Sacco System Australia Pty Ltd (Sacco) today announced a lead share agreement to introduce<\/p>\n                                <\/div>\n                            <\/div>\n                            <div class=\"footer\">\n                                <div class=\"read-more\">\n                                    <a href=\"https:\/\/saccosystem.com\/fr\/news\/list-biotherapeutics-and-sacco-system-announce-lead-share-agreement\/\">\n                                        Read Article                                    <\/a>\n                                <\/div>\n                            <\/div>\n                        <\/div>\n                        <div class=\"post post-extract\">\n                            <div class=\"header\">\n                                <div class=\"date\">\n                                    26 f\u00e9vrier 2024                                <\/div>\n                                <div class=\"tag\">\n                                    News, News                                <\/div>\n                            <\/div>\n                            <div class=\"body\">\n                                <div class=\"title\">\n                                    CSL FRANCE devient SACCO SYSTEM FRANCE                                <\/div>\n                                <div class=\"tags\">\n                                                                    <\/div>\n                                <div class=\"text\">\n                                    <p>Sacco System est le p\u00f4le biotechnologique international d\u00e9di\u00e9 \u00e0 l&rsquo;industrie alimentaire, nutraceutique pharmaceutique, bas\u00e9 sur la tradition&#8230;<\/p>\n                                <\/div>\n                            <\/div>\n                            <div class=\"footer\">\n                                <div class=\"read-more\">\n                                    <a href=\"https:\/\/saccosystem.com\/fr\/news\/csl-france-devient-sacco-system-france\/\">\n                                        Read Article                                    <\/a>\n                                <\/div>\n                            <\/div>\n                        <\/div>\n                        <div class=\"post post-extract\">\n                            <div class=\"header\">\n                                <div class=\"date\">\n                                    21 f\u00e9vrier 2024                                <\/div>\n                                <div class=\"tag\">\n                                                                    <\/div>\n                            <\/div>\n                            <div class=\"body\">\n                                <div class=\"title\">\n                                    Sacco System Supports Action4Diabetes&rsquo; mission                                <\/div>\n                                <div class=\"tags\">\n                                                                    <\/div>\n                                <div class=\"text\">\n                                    <p>We are proud to announce that Sacco System has made a significant donation in support of Action4Diabetes (A4D), mission\u2014a UK-based charity committed to ensuring free access to crucial medical supplies,<\/p>\n                                <\/div>\n                            <\/div>\n                            <div class=\"footer\">\n                                <div class=\"read-more\">\n                                    <a href=\"https:\/\/saccosystem.com\/fr\/news\/sacco-system-supports-action4diabetes-mission\/\">\n                                        Read Article                                    <\/a>\n                                <\/div>\n                            <\/div>\n                        <\/div>\n                        <div class=\"post post-extract\">\n                            <div class=\"header\">\n                                <div class=\"date\">\n                                    19 f\u00e9vrier 2024                                <\/div>\n                                <div class=\"tag\">\n                                                                    <\/div>\n                            <\/div>\n                            <div class=\"body\">\n                                <div class=\"title\">\n                                    Exploring a Future Without Stereotypes: SACCO SYSTEM at Liceo Scientifico Cavalleri for DYT                                <\/div>\n                                <div class=\"tags\">\n                                                                    <\/div>\n                                <div class=\"text\">\n                                    <p>This year too, SACCO SYSTEM proudly participates in the Deploy Your Talents (DYT) project, promoted by the Fondazione Sodalitas, with the patronage of the Municipality of Milan and in collaboration<\/p>\n                                <\/div>\n                            <\/div>\n                            <div class=\"footer\">\n                                <div class=\"read-more\">\n                                    <a href=\"https:\/\/saccosystem.com\/fr\/news\/exploring-a-future-without-stereotypes-sacco-system-at-liceo-scientifico-cavalleri-for-dyt\/\">\n                                        Read Article                                    <\/a>\n                                <\/div>\n                            <\/div>\n                        <\/div>\n                <\/div>\n            <\/div>\n        <\/div>\n        <div class=\"row\">\n            <div class=\"col\">\n                <div class=\"controls\"><\/div>\n            <\/div>\n        <\/div>\n    <\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Probiotics have been shown to effectively reduce the incidence of respiratory tract infections (RTIs). In particular, the strain Lactobacillus rhamnosus CRL1505 has demonstrated an important capacity to keep RTIs at<\/p>\n","protected":false},"featured_media":3312,"template":"","meta":{"_acf_changed":false},"category_news":[],"tag_news":[],"class_list":["post-5499","news","type-news","status-publish","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/saccosystem.com\/fr\/wp-json\/wp\/v2\/news\/5499","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/saccosystem.com\/fr\/wp-json\/wp\/v2\/news"}],"about":[{"href":"https:\/\/saccosystem.com\/fr\/wp-json\/wp\/v2\/types\/news"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/saccosystem.com\/fr\/wp-json\/wp\/v2\/media\/3312"}],"wp:attachment":[{"href":"https:\/\/saccosystem.com\/fr\/wp-json\/wp\/v2\/media?parent=5499"}],"wp:term":[{"taxonomy":"category_news","embeddable":true,"href":"https:\/\/saccosystem.com\/fr\/wp-json\/wp\/v2\/category_news?post=5499"},{"taxonomy":"tag_news","embeddable":true,"href":"https:\/\/saccosystem.com\/fr\/wp-json\/wp\/v2\/tag_news?post=5499"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}