{"id":8946,"date":"2025-02-04T12:44:53","date_gmt":"2025-02-04T11:44:53","guid":{"rendered":"https:\/\/saccosystem.com\/?p=8946"},"modified":"2025-03-26T15:42:33","modified_gmt":"2025-03-26T14:42:33","slug":"understanding-consumer-preferences-for-plant-based-food-alternatives-2","status":"publish","type":"post","link":"https:\/\/saccosystem.com\/en\/blog\/understanding-consumer-preferences-for-plant-based-food-alternatives-2\/","title":{"rendered":"Postbiotics (or inactivated microorganisms): the new frontier of health"},"content":{"rendered":"<div class=\"breadcrumbs style-1\"\">\n            <div class=\"row\">\n            <div class=\"col\">\n                <div class=\"pages\">\n            <span class=\"page parent\"><a href=\"https:\/\/saccosystem.com\/en\/blog-posts\/\">Blog<\/a><span class=\"separator\">&gt;<\/span><\/span><span class=\"page current\">Postbiotics (or inactivated microorganisms): the new frontier of health<\/span>                <\/div>\n            <\/div>\n        <\/div>\n    <\/div>\n\n<div class=\"title-style-blog\">\n            <div class=\"row\">\n            <div class=\"col\">\n                <h1>\n                    Postbiotics (or inactivated microorganisms): the new frontier of health                <\/h1>\n                <div class=\"blog-tags tags\">\n                    <div class=\"tag\"><a href=\"https:\/\/saccosystem.com\/en\/blog-posts\/\/?tag=probiotics\">Probiotics<\/a><\/div>                <\/div>\n                <h2 class=\"date\">\n                    04\/02\/2025                <\/h2>\n            <\/div>\n        <\/div>\n    <\/div>\n\n<figure class=\"wp-block-post-featured-image\"><img loading=\"lazy\" decoding=\"async\" width=\"2560\" height=\"1810\" src=\"https:\/\/saccosystem.com\/wp-content\/uploads\/2025\/02\/Postbiotici-scaled.jpg\" class=\"attachment-post-thumbnail size-post-thumbnail wp-post-image\" alt=\"I postbiotici (o microrganismi inattivati) cosa sono, i vantaggi\" style=\"object-fit:cover;\" srcset=\"https:\/\/saccosystem.com\/wp-content\/uploads\/2025\/02\/Postbiotici-scaled.jpg 2560w, https:\/\/saccosystem.com\/wp-content\/uploads\/2025\/02\/Postbiotici-300x212.jpg 300w, https:\/\/saccosystem.com\/wp-content\/uploads\/2025\/02\/Postbiotici-1024x724.jpg 1024w, https:\/\/saccosystem.com\/wp-content\/uploads\/2025\/02\/Postbiotici-768x543.jpg 768w, https:\/\/saccosystem.com\/wp-content\/uploads\/2025\/02\/Postbiotici-1536x1086.jpg 1536w, https:\/\/saccosystem.com\/wp-content\/uploads\/2025\/02\/Postbiotici-2048x1448.jpg 2048w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/><\/figure>\n\n\n<div class=\"wp-block-group row\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-group col-lg-8\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<p><\/p>\n\n\n\n<p>The use of <strong>postbiotics<\/strong>\u2014non-viable microorganisms with documented health benefits\u2014in the field of nutrition is opening up new and exciting possibilities. This frontier goes beyond traditional live probiotics and offers stable, versatile products suitable for innovative applications.<\/p>\n\n\n\n<p>Despite current gaps in regulatory frameworks and official definitions, the postbiotic sector and its related components are growing rapidly. This growth presents both challenges and opportunities that all stakeholders must be prepared to face.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Postbiotics (or inactivated microorganisms): what they are and their benefits<\/h3>\n\n\n\n<p><strong>Postbiotics and related terminology<\/strong><br>Also known as inactivated microorganisms, <strong>paraprobiotics<\/strong>, or <strong>tyndallized probiotics<\/strong>, postbiotics are non-viable microbial cells typically obtained through physical or chemical treatments. Although no longer alive, these microorganisms retain health-promoting properties.<\/p>\n\n\n\n<p>The debate surrounding the definition and scope of postbiotics has been ongoing. Over the years, various terms have been proposed\u2014such as inactivated microorganisms, paraprobiotics, or metabiotics\u2014to describe this category.<\/p>\n\n\n\n<p>In 2021, the <strong>International Scientific Association for Probiotics and Prebiotics (ISAPP)<\/strong> published a <strong>consensus statement<\/strong> aimed at clarifying the terminology. ISAPP defined a postbiotic as a &#8220;<em>preparation of inanimate microorganisms and\/or their components that confers a health benefit on the host<\/em>&#8220;, further specifying that &#8220;<em>to be effective, postbiotics must contain inactivated microbial cells or cellular components, with or without metabolites, that contribute to the observed health benefits<\/em>.&#8221;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Inactivation techniques<\/h3>\n\n\n\n<p>Microorganisms can be inactivated using a variety of methods, including heat treatment, UV radiation, high hydrostatic pressure, or chemical agents. The choice of inactivation method significantly affects the final properties of the product\u2014particularly its efficacy.<\/p>\n\n\n\n<p>For example, thermal inactivation\u2014one of the most commonly used techniques\u2014involves exposing microorganisms to high temperatures for a set period. This treatment makes postbiotics especially suitable for a wide range of formulations, from dietary supplements to cosmetics.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Main advantages of postbiotics<\/h3>\n\n\n\n<p>One of the key advantages of postbiotics over probiotics is their <strong>stability<\/strong>. Unlike live probiotics, postbiotics do not require refrigeration and generally offer improved shelf-life. This enhanced stability translates into greater <strong>formulation flexibility<\/strong> in nutritional supplements and functional foods, as well as <strong>greater accessibility<\/strong> in global markets with limited cold-chain infrastructure.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Regulatory challenges and future outlook<\/h3>\n\n\n\n<p>Despite growing interest, the regulatory framework for postbiotics is still evolving. Ongoing discussions among academia, industry, and regulatory authorities aim to establish how postbiotics should be defined, quantified, and characterized.<\/p>\n\n\n\n<p>This process also represents an opportunity to better understand their mechanisms of action and to identify <strong>more targeted applications<\/strong> for postbiotics.<\/p>\n\n\n\n<p>Research in this area is unlocking <strong>new opportunities<\/strong> for both science and industry. Postbiotics may prove to be a valuable alternative for individuals in fragile health or with conditions for which inactivated microorganisms are more appropriate than live ones.<\/p>\n\n\n\n<p>It is crucial that <strong>regulatory bodies<\/strong>, together with the <strong>scientific community<\/strong> and <strong>industry stakeholders<\/strong>, collaborate to create clear guidelines for the safe and effective use of these products in both human and animal health.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Conclusions<\/h3>\n\n\n\n<p>Integrating postbiotics into nutrition represents a promising area of innovation, offering clear advantages in terms of <strong>safety<\/strong>, <strong>stability<\/strong>, and <strong>product versatility<\/strong>. However, to fully unlock the potential of these ingredients, it is essential to address existing regulatory challenges and foster <strong>stronger collaboration<\/strong> between research institutions, the private sector, and relevant authorities. Only through a concerted approach can we ensure that consumers benefit safely and effectively from the opportunities offered by inactivated microorganisms.<\/p>\n\n\n\n<p>A more in-depth exploration of this topic is available in the article <em>\u201cInactivated Microorganisms and How to Describe Them \u2013 Postbiotics, Paraprobiotics and Other -biotics: Many Terms, Awaiting Guidelines\u201d<\/em> by <strong>Valentina Taverniti<\/strong>, published in <em>L\u2019integratore Nutrizionale<\/em> 3 \u2013 2024. The full article is available for download here: https:\/\/saccosystem.com\/wp-content\/uploads\/2024\/11\/IN273_Art_Taverniti.pdf.<\/p>\n<\/div><\/div>\n<\/div><\/div>\n\n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>The use of postbiotics\u2014non-viable microorganisms with documented health benefits\u2014in the field of nutrition is opening up new and exciting possibilities. This frontier goes beyond traditional live probiotics and offers stable,<\/p>\n","protected":false},"author":6,"featured_media":8987,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[165],"tags":[290],"class_list":["post-8946","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog-en","tag-probiotics"],"acf":[],"_links":{"self":[{"href":"https:\/\/saccosystem.com\/en\/wp-json\/wp\/v2\/posts\/8946","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/saccosystem.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/saccosystem.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/saccosystem.com\/en\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/saccosystem.com\/en\/wp-json\/wp\/v2\/comments?post=8946"}],"version-history":[{"count":0,"href":"https:\/\/saccosystem.com\/en\/wp-json\/wp\/v2\/posts\/8946\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/saccosystem.com\/en\/wp-json\/wp\/v2\/media\/8987"}],"wp:attachment":[{"href":"https:\/\/saccosystem.com\/en\/wp-json\/wp\/v2\/media?parent=8946"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/saccosystem.com\/en\/wp-json\/wp\/v2\/categories?post=8946"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/saccosystem.com\/en\/wp-json\/wp\/v2\/tags?post=8946"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}