{"id":4115,"date":"2023-01-18T12:50:44","date_gmt":"2023-01-18T11:50:44","guid":{"rendered":"https:\/\/saccosystem.com\/?p=4115"},"modified":"2024-12-09T17:09:22","modified_gmt":"2024-12-09T16:09:22","slug":"lactiplantibacillus-plantarum-p8-alleviates-stress-and-anxiety-and-improves-cognitive-function","status":"publish","type":"post","link":"https:\/\/saccosystem.com\/en\/blog\/lactiplantibacillus-plantarum-p8-alleviates-stress-and-anxiety-and-improves-cognitive-function\/","title":{"rendered":"Lactiplantibacillus plantarum P8 alleviates stress and anxiety and improves cognitive function"},"content":{"rendered":"
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\n Blog<\/a>><\/span><\/span>Lactiplantibacillus plantarum P8 alleviates stress and anxiety and improves cognitive function<\/span> <\/div>\n <\/div>\n <\/div>\n <\/div>\n\n
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\n Lactiplantibacillus plantarum P8 alleviates stress and anxiety and improves cognitive function <\/h1>\n
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Anxiety<\/a><\/div>
Probiotics<\/a><\/div>
Stress<\/a><\/div> <\/div>\n

\n 18\/01\/2023 <\/h2>\n <\/div>\n <\/div>\n <\/div>\n\n
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Stress<\/strong> is a psychological and physical response to challenges and demands that under some conditions can stimulate us and guide us in solving problems, known as eustress<\/strong>. However, in many cases stress can come from emotionally challenging experiences <\/strong>or seemingly minor and routine everyday life events, from a traffic jam to tight work deadlines, that when accumulated can be detrimental to our health<\/strong>. Strong bouts of stress or prolonged stress can compromise our well-being and trigger anxiety that, if left untreated, can lead to more serious disturbances such as depression, which affects more than 300 million people worldwide.<\/p>\n\n\n\n

Stress <\/strong>causes a prolonged rise in glucocorticoid levels<\/strong>, which progressively impairs the immune system and hippocampal structure, leading to alterations in neurogenesis<\/strong> and neuronal morphology. Furthermore, stress is also associated with increased risk of cardiovascular disease<\/strong> and metabolic and gastrointestinal pathologies.<\/p>\n\n\n\n

Accumulating evidence on the role of gut bacteria on mental health<\/strong> has made scientists to start considering the gut microbiota as an \u201cendocrine organ\u201d, leading to the concept of \u201cgut-brain axis<\/strong>\u201d, a dynamic and bi-directional system of communication involved in maintaining homeostasis. For example, germ-free mice have higher levels of plasma corticosterone and anxiety behaviors, indicating the key role of the gut microbiota in mental health and host behaviors.<\/p>\n\n\n\n

This binary interaction <\/strong>does not only impact our mental health, but also several other aspects of our physiology<\/strong>, such as glucose homeostasis, satiety, obesity, gastrointestinal and inflammatory disorders. Elements of the gut-brain-axis include signal molecules (cytokines, hormones, and neuropeptides) involved at nervous (central and enteric nervous system), hormonal and immune level.<\/p>\n\n\n\n

Over the last years, there has been an increasing interest on the impact of probiotic intake in mental health<\/strong>: certain strains have shown potential as therapeutics or adjuvants in the treatment of stress<\/strong> and anxiety<\/strong> through the direct production of bioactive molecules, or through the modulation of specific pathways of the gut-brain axis.<\/p>\n\n\n\n

Lactiplantibacillus plantarum P8<\/strong> (basonym Lactobacillus plantarum<\/em>) was isolated from a traditionally fermented sour milk in Inner Mongolia, China, and is produced by Sacco<\/strong>. P8 has been deeply studied since 2005 for its excellent probiotic properties<\/strong>, including its effect on the gut-brain axis in adults, highlighting its significant benefits in reducing stress and anxiety<\/strong>, together with improving cognitive and memory functions<\/strong>.<\/p>\n\n\n\n

For clinical evidence of P8<\/strong>\u2019s efficacy and effects on the Gut-Brain Axis<\/strong>download the full study<\/strong>.<\/p>\n<\/div><\/div>\n<\/div><\/div>\n\n\n\n

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\n Attached resources <\/h2>\n
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\n \n \n \n <\/rect><\/mask><\/path><\/g><\/svg> <\/span>\n \n \n Lactiplantibacillus plantarum P8 <\/span>\n <\/span>\n <\/span>\n \n \n \n \n <\/rect>\n <\/mask>\n \n <\/path>\n <\/g>\n <\/svg>\n <\/span>\n Download\n <\/span>\n <\/a>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>","protected":false},"excerpt":{"rendered":"

Stress is a psychological and physical response to challenges and demands that under some conditions can stimulate us and guide us in solving problems, known as eustress. However, in many cases stress can<\/p>\n","protected":false},"author":1,"featured_media":3414,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[165],"tags":[282,290,292],"class_list":["post-4115","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog-en","tag-anxiety","tag-probiotics","tag-stress-en"],"acf":[],"_links":{"self":[{"href":"https:\/\/saccosystem.com\/en\/wp-json\/wp\/v2\/posts\/4115","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/saccosystem.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/saccosystem.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/saccosystem.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/saccosystem.com\/en\/wp-json\/wp\/v2\/comments?post=4115"}],"version-history":[{"count":0,"href":"https:\/\/saccosystem.com\/en\/wp-json\/wp\/v2\/posts\/4115\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/saccosystem.com\/en\/wp-json\/wp\/v2\/media\/3414"}],"wp:attachment":[{"href":"https:\/\/saccosystem.com\/en\/wp-json\/wp\/v2\/media?parent=4115"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/saccosystem.com\/en\/wp-json\/wp\/v2\/categories?post=4115"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/saccosystem.com\/en\/wp-json\/wp\/v2\/tags?post=4115"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}